Salmon DNA Injection Therapy: A Breakthrough in Regenerative Skincare
What Is the Salmon Needle Treatment?
Also known as Salmon DNA Therapy, the Salmon Needle is an innovative cosmetic procedure that utilizes a compound derived from the DNA of salmon. This compound, rich in Polydeoxyribonucleotide (PDRN), is a biologically active molecule renowned for its regenerative, anti-inflammatory, and healing capabilities. It promotes collagen synthesis, accelerates cell renewal, minimizes signs of aging, and helps improve the appearance of scars by stimulating tissue regeneration.
Origins in Medicine
Initially introduced in 2008, Salmon DNA serum gained traction in the field of regenerative medicine, especially for wound care and post-graft skin healing. Its proven efficacy in promoting rapid tissue repair led to its integration into aesthetic dermatology, where it is now widely used for skin revitalization.
How Does It Work?
Salmon DNA injections contain highly purified PDRN molecules, typically ranging from 50–150 kDa in molecular weight. These are extracted from the sperm cells of salmon through a meticulous high-temperature purification process, ensuring maximum potency and biocompatibility.
The treatment activates cellular regeneration by stimulating fibroblasts—the cells responsible for producing collagen, elastin, and capillaries. This leads to significant improvements in skin firmness, texture, hydration, and radiance.
Key Benefits
Stimulates Collagen Production for firmer, youthful-looking skin
Refines Skin Texture and smoothens rough patches
Reduces Fine Lines and Wrinkles
Improves the Appearance of Scars including acne marks and stretch marks
Balances Sebum Production and evens skin tone
Boosts Skin Elasticity and Hydration
Strengthens the Skin Barrier against environmental stressors
Calms Inflammation and enhances natural healing
Safe and Biocompatible, with a low risk of adverse effects
Treatment Procedure
The skin is thoroughly cleansed and disinfected.
A topical anesthetic is applied to ensure comfort.
PDRN is injected into targeted areas using ultra-fine needles.
Injection depth and pattern are tailored to the specific skin concern.
Mild redness or itching may occur post-treatment, typically resolving within hours.
Versatile Applications
Facial Rejuvenation: Smoothes fine lines and refreshes dull, tired skin
Hair Restoration: Stimulates hair follicles, encouraging healthier, thicker hair
Scar and Wound Healing: Accelerates tissue regeneration and minimizes scar visibility
Treatment Plan & Results
Noticeable improvements are often seen after the first session. For best results, a series of 3 to 6 sessions spaced 3–4 weeks apart is usually recommended, depending on the individual’s skin needs. Each session typically lasts between 15 and 60 minutes.
Results are long-lasting, with maintenance sessions suggested every 6–12 months to preserve the skin’s youthful appearance.
Why Choose Salmon Needle Therapy?
Clinically Proven & FDA-Approved
Biocompatible and Non-Toxic
Minimal Downtime and non-invasive
Effective Long-Term Skin Rejuvenation
Potential Side Effects
While generally well-tolerated, some individuals may experience:
Temporary redness or mild swelling at the injection site
Light bruising
Rare allergic reactions
Aftercare Guidelines
To optimize outcomes and reduce any side effects, follow these post-treatment care tips:
Avoid applying makeup for at least 24 hours
Shield your skin from UV rays; use SPF 30+ sunscreen
Stick to gentle, fragrance-free moisturizers
Refrain from using saunas, jacuzzis, or engaging in intense workouts for 48 hours
Schedule maintenance sessions every 6–12 months as advised by your practitioner
Salmon DNA vs. Skin Booster Injections
While both enhance skin health and appearance, their modes of action differ:
Skin Boosters contain hyaluronic acid, which hydrates and plumps the skin
Salmon DNA Injections offer deeper skin repair by regenerating tissue and boosting collagen
For optimal results, these treatments can be combined based on individual goals and skin assessments.
Can Salmon DNA Be Combined with Other Aesthetic Procedures?
Absolutely. Salmon DNA Therapy pairs well with a variety of cosmetic treatments and may amplify their benefits. Common combinations include:
Ulthera or Thermage FLX – for skin tightening
Microneedling, CO2, or Fraxel Dual Lasers – for texture refinement and scar treatment
EMTONE – for reducing cellulite and improving skin tone
Your skincare provider will customize a treatment plan to align with your aesthetic goals.